HPE ProLiant DL380 Gen10 8SFF Server – Xeon Gold 5118, 64GB DDR4, 8-Bay SFF, Dual 800W PSU

The HPE ProLiant DL380 Gen10 8SFF P06422-B21 server offers powerful performance, next-gen security, and exceptional scalability for modern data centers. Powered by an Intel® Xeon® Gold 5118 processor and equipped with 64GB DDR4 memory, this 2U rack server is engineered for versatility—whether you’re deploying on-premise, in the cloud, or in a hybrid IT environment. Its modular 8-bay Small Form Factor (SFF) design, dual redundant 800W power supplies, and support for up to two CPUs make it ideal for virtualization, AI, deep learning, and big data analytics.

Product Features

Adaptable Storage and Expansion Options

The DL380 Gen10 supports up to 30 SFF, 19 LFF, or 20 NVMe drives, allowing enterprises to scale storage easily. This configuration comes with 8 SFF hot-swappable bays, ideal for performance-driven storage and expansion. You can also add double-wide GPUs or use PCIe risers for more specialized workloads.

Enterprise-Class Compute Power

At the core of this system is the Intel® Xeon® Gold 5118 processor with 12 cores and 24 threads, operating at 2.3 GHz. The platform supports up to two processors, enabling advanced compute density and workload efficiency.

Scalable High-Speed Memory

Equipped with 64GB DDR4 SDRAM, expandable up to 3TB across 24 DIMM slots, the DL380 Gen10 supports HPE Persistent Memory, combining DRAM and storage for ultra-fast data processing—ideal for databases and analytics.

Advanced Security Architecture

HPE’s Silicon Root of Trust, Server Configuration Lock, and Runtime Firmware Verification deliver end-to-end security from boot to firmware. Enhanced features like iLO 5 Security Dashboard and Secure Recovery provide visibility and integrity throughout the server lifecycle.

Optimized for AI, ML, and VDI

With enhanced GPU density, support for up to 7 single-width GPUs or 6 full-height GPUs, and compatibility with NVIDIA T4, this server is a go-to solution for deep learning, virtual desktops, and hybrid workloads, offering cost-effective compute acceleration.

Intelligent Management Tools

Benefit from lifecycle tools like UEFI, Intelligent Provisioning, HPE iLO 5, Smart Update Manager (SUM), and Service Pack for ProLiant (SPP). These streamline deployment, monitoring, and firmware updates, reducing IT overhead.

Redundant, Efficient Power Supply

Comes with 2 x 800W redundant power supplies, offering failover protection and high efficiency under variable load conditions. Perfect for 24/7 enterprise environments requiring consistent uptime.

Product Specifications

• Processor: Intel Xeon Gold 5118 (12-core, 2.3 GHz)
• Memory: 64 GB DDR4 SDRAM (2 x 32 GB), expandable to 3 TB
• Drive Bays: 8 x 2.5″ SFF hot-swap (no drives included)
• Controller: HPE Smart Array P408i-a SR Gen10 (12Gb/s SAS, RAID support)
• GPU Support: Up to 7 single-width or 6 full-height GPUs
• Network: Embedded 4 x 1GbE, FlexibleLOM support (up to 40GbE)
• Expansion Slots: Multiple PCIe 3.0 slots for additional networking/storage
• Power: Dual 800W redundant PSUs
• Form Factor: 2U Rackmount
• Dimensions: 17.5″ W x 3.4″ H x 26.7″ D
• Weight: Varies by configuration
• Operating System: Not included; supports Windows, VMware, RHEL, SLES, ClearOS, and more
• Energy Efficiency: ENERGY STAR Certified

Ideal Use Cases

• Virtualization (VMware, Hyper-V)
• Artificial Intelligence (AI) and Machine Learning (ML)
• Database and Big Data Analytics
• Private Cloud and Hybrid Deployments
• Virtual Desktop Infrastructure (VDI)